Based on the analytical solution of infinitely aquifer and linear impervious boundary case, The Simplex-chaos optimization algorithm is applied in the analysis of pumping experiment data to estimate the aquifer parameters. Such measures as adding Simplex algorithm into Chaos optimization algorithm are taken to improve convergence of algorithm. The results show that the method can be successfully applied to solve the aquifer parameter function optimization problem; the range of initial guess value of aquifer parameters has influence on the convergence speed of the algorithm, but has no effect on the final result of computation; in comparison with the chaos optimization algorithm, the combined algorithm has the advantages of rapid convergence rate and high accuracy.