The conventional river health assessment system mainly focuses on the aspects of “basin”, “water,” biology and social service functions, lacks the integration of information technology methods and fails to meet the requirements of the rapid development of water conservancy information technology. Regarding to these disadvantages, relevant indicators of river informatization was introduced to construct a river health assessment system that considers the river information service capability by means of analytic hierarchy process and entropy weight method. There were 18 indicators in the evaluation system, from aspects of hydrology, water quality, biology, habitat physics, social service function and information service capability, and the comprehensive fuzzy evaluation system was utilized to evaluate the river health status. The feasibility of this system was verified by the case study of the river health assessment of the Zhuangmu River. By integrating information service capability, the evaluation frequency was increased, which changed the previous passive evaluation into active push and active acquisition, and realized the upgrade of river and lake health management methods and capabilities.