In order to investigate the response charateristics of the growth, physiology and yield of the edible rose (Rosa rugosa Thunb.) to the irrigation methods and fertilization rates, the complete combinations of two different irrigation methods (micro-sprinkler irrigation, W; drip irrigation, D) and 4 fertilization rates (F0=0, F1=60, F2=135 and F3 = 225 kg/hm2) were tested using a 2-year-old edible rose cutivar “crimson glory” as the experimental material. The results showed that the irrigation method and fertilization rate had a significant effect on the plant height and stem diameter of “crimson glory” (P<0.05), WF3 treatment was beneficial to the plant height growth of “crimson glory”, whereas DF3 treatment was conducive to the stem diameter. At all growth stages, irrigation methods and fertilization rates had a significant effect on the net photosynthetic rate of the edible rose (P<0.05), and the net photosynthetic rate and transpiration rate of the edible rose peaked at the budding stage, with the net photosynthetic rate reaching the highest (17.93 μmol/( m2·s)) under DF2 and the transpiration rate achieving the highest(6.10 mmol/( m2·s)) under DF3 treatment. Moreover, the interaction between the irrigation method and fertilization rate had a significant effect on the carotenoid content and chlorophyll content of the edible rose leaves (P<0.05), and the contents of chlorophyll and carotenoids were relatively high under DF2 and DF1 treatment, which were 1.83 and 0.30 mg/g, respectively. The total yield of the edible rose under drip irrigation was higher than that under micro-sprinkler irrigation, which increased first and then decreased with the increase of the fertilization rate. In addition, the total yield of DF2 treatment was the highest (11 036 kg/hm2), indicating that DF2 is the suitable combination of irrigation method and fertilization rate for “crimson glory” under the condition of rain shelter greenhouse.