Based on the daily precipitation data of the middle and upper reaches of the Wujiang River from 1961 to 2019, the spatio-temporal characteristics of extreme precipitation were studied using trend analysis, EOF and wavelet analysis. At the same time, in order to make the study holistic, three scenarios (SSP126, SSP245 and SSP585) under five GCMs in CMIP6 were used to estimate future precipitation changes (2020-2100) after downscaling. The results show that the extreme precipitation has increased and decreased in the past 59 years with insignificant changes. In terms of the change cycles, the cycle of strong signal mainly concentrated on the time scale of 23-30 a and ran through the whole time series. In the first mode, the changes of the five extreme precipitation indices were consistent spatially, but differentiated in the second mode. In general, the future extreme precipitation events will increase with the increase of SSP scenarios, and the trend is mainly positive. The research results can provide some reference for water security control, planning and construction, disaster prevention and mitigation in the Wujiang River Basin.