Aiming at the deformation and failure characteristics of high piled wharf structures under the condition of continuous siltation of the bank slope, we established the wharf-slope coupled models of the whole structure and the single-bent structure respectively using finite element method. The displacement variation of the wharf pile foundation with the process of bank slope siltation was studied. The results show that the structure mainly experiences vertical displacement with an incline towards the shore at its back. The horizontal displacement of the pile top is obviously smaller than that of the lower part of the pile. Due to the curvy shape of the pile body, the least favorable position of stress is at the top of a pile. The simulation result of the single-bent model is closer to that of the middle bent of the whole structural model, with the maximum deviation barely reaching 5.46%. Thus, the single-bent model can significantly improve the calculation efficiency, but it is unable to reflect the differences of deformation results in different bent positions.