In recent years, the frequent occurrence of urban floods has attracted attention from experts and scholars of related fields. The ArcGIS technology and fuzzy comprehensive evaluation method were used to carry out the risk assessment and zoning of urban storm water flood disaster in Shenzhen City which suffers from frequent flooding, based on the factors of risk and vulnerability according to the theory of disaster system. In the analysis, factors such as disaster causing factors, disaster inducing environment, disaster bearing body, the capability of disaster prevention and mitigation were considered comprehensively. Finally the storm water flood disaster risk zoning map was generated with 100 m×100 m as the basic evaluation unit. The results show that the high risk areas of flood disasters in Shenzhen City mainly distributed in western Bao’an District, Futian District, western Luohu District, Longgang District and parts of Dapeng New District. The research results can reflect the actual distribution of flood disaster risk in Shenzhen City, therefore it can provide a scientific basis for flood disaster management, prevention and mitigation work of the departments concerned.