The generalized watershed loading function (GWLF) has been widely recognized as a simple and effective lumped parameter watershed model by researchers at home and abroad. On the basis of the previous work of the authors, the original GWLF model algorithm and the existing hydrological framework were further modified with the addition of the suspension and deposition process of sediment, and the attenuation process of pollutants in the river channel, which enhanced the applicability of the model spatially. Then the revised GWLF model was tested in the simulation of the upstream of Xin′anjiang River (bounded by Tunxi monitoring station) in Anhui Province and the simulation results of monthly flow, sediment, dissolved nitrogen and dissolved phosphorous were compared with those of the original model. The time series analysis of three commonly used statistical indexes show that the revised model performs better at reflecting the cycle of hydrology, sediment and water quality in the watershed without the requirement of additional data.