Mike model can be used to simulate urban and basin water environment, water resources, water security and water ecology. The software has been widely used in practical engineering domestic and abroad as a result of powerful functions and user-friendly interface. The basic principles, characteristics and application scope of MIKE11, MIKE21, MIKE FLOOD, MIKE URBAN, MIK E BASIN and MIKE SHE models are summarized. The functions of the main models are compared, and the application of each model and its different combinations in practical engineering is summarized. Finally, the limitations of the MIKE model are proposed and the future development direction of the model is prospected, in order to provide a reference for the MIKE model to be better applied to practical problems.