Based on the daily precipitation data of 19 meteorological stations in Henan Province of the latest 57 years from 1960 to 2017, the standardized precipitation index (SPI) was calculated. The spatial and temporal characteristics of drought in Henan Province were studied in terms of monthly, interannual and periodic dimensions by the fuzzy C-means clustering and wavelet analysis. The results showed that all meteorological stations could be divided into three regions: southeastern Henan, northern Henan and western Henan. There was a continuous drought in 1966, 1986 and 1997 for the whole Henan Province. The longest continuous drought period in southeastern Henan was 10 months and drought prone in summer. The longest continuous drought period in northern Henan was 9 months and it was prone to severe drought. The continuous drought periods in western Henan was the most, but the longest scale was 7 months. Drought frequency was mainly distributed in northern Henan, followed by western Henan, and the least in southeastern Henan, but it was more than 30% and more uniform among regions after the 1990s. The main cycle of 23~25, 20~22 and 15~17 years were drought prone in southeast Henan, northern Henan and western Henan, respectively.