To study the migration and transformation of pollutants As in soil, reclaimed water drip irrigation experiments were conducted during the growth of greenhouse vegetables, using underground water irrigation as the contrast treatment. The distribution and migration of As accumulation in different depths of soil in 7 days after drip irrigation were analyzed. The results showed that: on the first day after drip irrigation, the As concentration in the soil surface was the highest, and the As concentration at the depth of 100 cm was the highest on the third day after drip irrigation. The As concentration in the surface soils slightly decreased. From the fifth day to the seventh day, the concentration of As at the depth of 80-120 cm is the highest, while the As concentration decreases slightly with the depth of the As at the depth of less than 120 cm. With the increase of irrigation frequency, the accumulation of As in surface soil increased during the growing period and after the growing period, but the amount of 80-120 cm soil increased less and the concentration of 200 cm decreased. The proper concentration of reclaimed water drip irrigation condition, soil deep layer As concentration in line with soil environmental quality standard limits, the proper concentration of reclaimed wastewater irrigation will not cause pollution of As.