A large number of pollutants infiltrate into the groundwater with the rainfall runoff due to the rapid development of industry and agriculture. Due to certain difficulty and high economic cost of the real-time monitoring, groundwater simulation software is developed. This paper systematically analyzes the structure, solution methods, function, and advantages and disadvantages of such groundwater simulation software as GMS, FEFLOW, Visual MODFLOW, MT3DMS, and TOUGH2. The numerical simulation application of this software in the field of groundwater flow, water level and migration of pollutants is summarized. Finally, the development trends of the software are put forward, which are the integration with 3S technology, the combination with artificial neural network prediction method, climate change model, multiphase model, the development of the coupling model of surface water-groundwater and the optimization of model structure. This paper can provide supports for the simulation of groundwater hydrodynamic and pollutant transport and the construction of the sponge city in China.