With the development and utilization of offshore wind power, the collision risk between the ship and offshore wind turbine is gradually rising. Therefore, the nonlinear finite element LS-DYNA simulation software is used to simulate the collision process of a 5000 t ship at a speed of 2 m/s with a typical 3 MW monopile offshore wind turbine and to study the influence of the wind load on the collision between ship and monopile wind turbine. Through the analysis of collision force, displacement and acceleration of the top in tower and equivalent plastic strain at the tower, the result can be obtained as follow: the wind load on the wind turbine has great influence on dynamic response of collision; relative difference of the collision force, displacement and acceleration of the top in tower and equivalent plastic strain at the tower are about 1%, 10.9%, 17.5% and 3.05%, respectively. The direction of wind load has also great influence on dynamic response of collision; in the different direction of the wind load, the maximum and minimum of the collision force, displacement and acceleration of the top in tower and equivalent plastic strain at the tower are about 28.5%, 57%, 62.5% and 28.5%, respectively. In the different direction of the wind load, the maximum and minimum of longitudinal displacement are 0.505 m and 0.0393 m, respectively. The results of the study can provide theoretical reference to provide the offshore wind turbine in the collision.