The hydrological cycle element observed under environmental change has taken place significant trend change. The influence and response of climate, vegetation coverage and hydrological cycle process has become a frontier scientific issue studied in global change. The paper systematicly reviewed climate change, hydrological cycle and, vegetation coverage variation and hydrology process, and the progress of vegetation coverage change and hydrological responses driven by climate change. Finally, the paper further discussed the scientific issue and main research content in response of climate, vegetation coverage change and hydrological cycle.