In order to study the feature of non-point source pollution in control sections of upstream and downstream river,and the characteristics of non-point source pollution in the same section of different years,the paper took Dayukou section of Fenghe river upstream and Qinduzhen section of Fenghe river middle stream which is the tributary of Weihe River as the object of study,and analyzed the feature of non-point source pollution in control sections of upstream and downstream rive according to the synchronous data of water quality and quantity from 2009 to 2011 by using the mean concentration method to estimate the load of non-point source pollution and combining the different basin situations of human activities and land types.The result shows that non-point source pollution is the main pollution of Fenghe River . The load proportion of non-point source pollution in upstream section of river is larger than that in downstream section of river; it is basic equivalent for the non-point source pollution concentration between upstream and downstream sections of the river, but the point source pollution concentration in downstream section is higher than ithat in upstream section; the non-point source load of COD,TP and NO2-N in downstream section is10-20 times that in upstream section;the point source pollution produced by human activities has greater influence on water quality in middle and downstream sections of river.