Hydrodynamic process in Poyang Lake from 2009 to 2011 was simulated by using the lake hydrodynamic model, EFDC. Results showed that simulated daily average water elevation and discharges consisted with hydrologic station observations and the correlation coefficients are all above 0.94.Remote sensing data were employed to validate and analyze the model practicability more comprehensively in order to solve the problem of data deficiencies. The water surface height and inundation area measured by Radar altimeter ENVISAT RA-2 and MODIS images correlated with numerical simulation resultswith a correlation coefficient higher than 0.83, which indicated that thefrequently changingwater dynamic characteristics in Poyang Lakecould be effectively revealed by using EFDC model.Furthermore, remote sensing techniquesalso providedtheory for long-termvalidation from different perspectives.