In order to understand the dynamic change of water quality and according to the actual data of main pollution indices of surface water quality in Jiangyin from 2006 to 2011, the paper used the seasonal Kendall method to analyze the variation tendency of main pollution indices of surface water in Jiangyin. The results showed that in recent years, with the implement of prevention and control of water pollution in Jiangyin, the situation of water quality of major rivers and lakes in Jiangyin shows improving trends.