Farmland wastewater is the main non-point source pollution in Bosten Lake. Based on the characteristics of pollutant source in Bosten Lake area and the dynamic hydrological conditions, the paper applied water quality response model plan couple method. Under the plan objective conditions of meeting the water function area, the amount of pollutant from point and non-point source witch flow into the lake is totally fixed.The water environmental capacity determined in the absence of irrigation and wastewater discharge is point source control quota.The total control quota of point and non-point source defined by subtracting the total point source control quota equals to the total amount of non-point source control quota. Through the above-described method, the total amount of point and non-point source control Quota for Bosten lake was gotten . The result can provide a theoretical basis for the control of total amount of point and non-point source pollutants.