Owing to the conflict between the increased water demand and water shortage, water resources has become a bottleneck of regional social and economic development. Based on the precondition of clear water supply quantity, the water demand can be satisfied by improving the efficiency of water use, and preventing water pollution, so that the new idea of water management can be achieved though the transition from traditional water supply management to water demand management. Taking Jiangsu province as the study object on the visual angle of water demand management, this paper analyzed the key indexes that affect water demand from the three aspects of production, domestic and ecological water by Delphi method. It diagnosed by factor analysis that the common factors of water demand driving forces are the factors of agriculture, economic development, population and ecology. The research will offer the decision-making basis for the optimization of regional water structure and the implementation of the strictest water resources management system.