To investigate the effect of soil density on soil water infiltration and yield of drip-irrigated maize under film mulching, field experiments were carried out. The effects of three soil densities on the soil mass under two-point source infiltration were analyzed from aspects of wetted body shape, wetted body volume, spatial soil moisture content, maize yield, water use efficiency (WUE) and irrigation water use efficiency (IWUE). The results show that soil density is the main factor affecting soil moisture change and maize yield when other conditions, such as drip irrigation flow and irrigation time are given. With the increase of soil density, the horizontal diffusion distance, the volume of wetted body and the area of intersection interface all increase; whereas the vertical infiltration distance and the average moisture content of soil at the intersection interface all decrease. Meanwhile, soil water distribution uniformity coefficient (Cu), maize yield, WUE and IWUE all increase first and then decrease; while Euclidean distance decrease first and then increase. When the soil density is 1.564 g/cm3, the wetted body Cu reaches the highest (93.7%), the Euclidean distance become the shortest (0.09), and the maize yield, WUE and IWUE all reaches the highest (13,796.68 kg/hm2, 2.98 kg/m3 and 4.50 kg/m3). The results of this study can provide a strong technical support for the research on improving the application effectiveness of maize drip irrigation under film, and a practical guidance for the design of the drip irrigation project of high-standard farmland construction in Shiyang River Basin.