In order to evaluate the effect of alpine region environment on the freeze-thaw cycle durability of hydraulic concrete structures with mineral mixed admixtures, the freeze-thaw cycles of hydraulic concrete with different mixture amount, mixture type, and freeze-thaw temperatures were studied and analyzed. The time-varying laws of mass loss rate, relative dynamic elastic modulus, compressive strength and permeability of hydraulic concrete with different mixing ratios were studied and analyzed, and the influence mechanism of mineral admixtures and freeze-thaw temperature on the frost resistance of concrete was revealed. The test results showed that the frost resistance of concrete with different admixtures ranked: fly ash + silica fume + rice husk fume > silica fume + rice husk fume > fly ash + silica fume > fly ash + silica fume > fly ash + rice husk fume > rice husk fume > silica fume > fly ash > without addition. Under the same single mixing condition, the test group with rice husk ash had the highest frost resistance, the silica fume was in the middle, and the fly ash was the weakest. For mineral mixed admixtures with several minerals, three of fly ash, silica fume and rice husk ash have the strongest frost resistance. Mixed mineral admixtures can reduce the porosity and permeability of hydraulic concrete, and different particle sizes of fly ash, silica fume and rice husk ash will fill each other, resulting in superimposition effect. The freeze-thaw damage of hydraulic concrete increases with the decrease of central temperature during freeze-thaw cycles, which is mainly due to the increase of temperature gradient in concrete and expansion pressure in pore.