The hydrological model is one of the important tools for reservoir flow simulation. Taking the Chengping First Grade Reservoir in Suichang, Zhejiang Province as the research object, the flow rate simulation was carried out based on the LH-OAT method, the DE method and the HYPE model,. The availability of the model was evaluated through parameter sensitivity analysis, parameter calibration and error analysis. The Conclusions are as follows:The most sensitive parameter in the HYPE model is cevp, and other sensitive parameters include: pcluse, cevpcorr, rrcscorr and rrcs1. The Nash-Sutcliffe efficiency (NSE) is 0.87 in calibration period by the HYPE model, and is 0.83 in verification period, which show the high capacity of the HYPE model on long sequence hydrologic simulation. The simulation value was lower than the measured value in the flood peak simulation by the HYPE model, and the possible reason may be the low accuracy of input parameters was insufficient to reveal the rainstorm basin characteristics. Using the new parameters to describe the rainstorm characteristics resulted improved simulation.