In order to explore the high yield, high efficiency and water saving irrigation system of drip irrigation maize under mulch and solve the severe problem of lacking of related irrigation system in drip irrigation maize in the area of multiple gravel sandy soil, this paper studies the effect of different irrigation quota（300m3/hm2(W1)、375m3/hm2 (W2)、450m3/hm2 (W3)、525 m3/hm2 (W4)、600 m3/hm2 (W5)）on physiological index, yield and water use efficiency of maize by means of field plot contrast test. The results showed that increased irrigation quota can promote physiological index of maize and accelerate grain development. Irrigation quota and yield, water use efficiency showed a single peak curve change, and have a linear relationship with water consumption. When irrigation quota was more than 525 m3/hm2, physiological index and yield had no significant influence. When the irrigation norm was less than 450 m3/hm2, the growth and development of crops was inhibited, the yield components were seriously affected, and the final yield of maize was restricted. Under the W4 treatment, the yield and water use efficiency reached the peak. The comprehensive test and analysis showed that the irrigation schedule with irrigation quota of 525 m3/hm2 was more suitable in the multiple gravel sandy soil area.