Taking the granite in Shuitou Town, Annan City, Fujian Province as the research object, the physical and mechanical prosperities of granite in different acid solutions (pH = 1, pH = 3, pH = 5) under different immersion time （30d，60d，90d）were analyzed under uniaxial compression The morphology of the damaged granite sample is observed by using scanning electron microscope and the constituent of the damaged granite samples are detected by using X-ray diffraction. The microscopic damage of granite after chemical solution corrosion is discussed. The results show that the physical and mechanical properties have degradation after chemical corrosion. With the decrease of the PH value of chemical solution, Young's modulus and peak stress of granite decline. With the increase of chemical corrosion time, Young's modulus and peak stress of granite decline. The connection of minerals in granite decreases with the increase of the immersion time and elevated PH value by observing SEM pictures.