A variety of statistical methods such as wavelet analysis were used to have a thorough grasp of the variation characteristics of air temperature and precipitation from 1956 to 2015, of the recent 60 years, in Gaoyou City from the aspects of trend, mutation and period. The results showed that the air temperature in Gaoyou City has been on the rise generally in the past 60 years at a linear rate of about 0.30℃ per 10 years. The mean annual air temperature started to fluctuate in an upward trend in the mid-1980s, while the annual precipitation fluctuated steadily with a slight linear increase rate of about 2.2 mm per 10 years; the warming mutation of the air temperature was detected to appear around 1998 by moving t-test and Mann-Kendall test, while the mutation of the precipitation was not detected; Morlet wavelet transformation showed that the periodicity of the mean annual air temperature is the most remarkable at the time scale of 55 years, and the annual precipitation had four obvious periodic oscillations, which are 56 years, 43 years, 20-30 years and 9 years. The periodic oscillation seemed to be the strongest at the time scale of 55 years and the weakest at the time scale of 20-30 years; the main period of the air temperature is consistent with the first main period (56 years) of the precipitation.