The selection of operation plan of well group pumping station will directly affect the operation cost of pumping station. The nonlinear energy equations of parallel operation of pump in group pumping station are established. The Newton iteration method is used to solve the parallel pump operating point, and the two unit power price is used to calculate the corresponding water consumption and electricity bill. The linear programming model of optimal operation scheme is established by taking the minimum power consumption of the pumping station as the objective function. The results show that the running time of the single water consumption and low electricity tariff scheme in the optimized operation scheme is long and conforms to the expectation; the optimal scheme under the design of water supply scale saves 5.14% of the daily electricity consumption compared with the original scheme. It has guiding significance for similar projects to achieve efficient and economical operation.