In order to analyze the dynamic response characteristics of monopile wind turbine collision with ship, a 3MW wind turbine and ship collision model based on monopile was established. Based on explicit dynamical theory and nonlinear finite element method, simulation of the dynamic response of the wind turbine by 5000-t by the LS-DYNA at different impact speed was conducted. The results showed that: the duration of the collision and the maximum contact force increases with speed; after the collision, the ratio of the ship rebound kinetic energy to the initial kinetic energy decreases with the increase of speed , but the ratio of the structure deformation energy to the initial kinetic energy increases as the speed increases; When the ship speed is 2 m/s, the collision is mainly plastic collision, the collision depth is 0.675m, and the top tower wind turbine maximum displacement and acceleration are 2.3m and 29 m/s2.