To assess the benefits of wetland replenishment project comprehensively, based on the research and analysis of ecological status of wetlands, the paper established the index system of comprehensive benefit evaluation for wetland replenishment project which included three primary indicators and twelve secondary indicators. Furthermore,the paper applied the model combining entropy and grey correlation analysis to the assessment of wetland replenishment project.In order to verify the feasibility of the assessment method, this paper selected three typical wetland replenishment projects,and used expert scoring method to obtain the original data. the results show that the constructed indicator system is reasonable, and the combined model of entropy method and grey correlation analysis can scientifically assess the effects of implemented wetland replenishment project.