To master the climatic variation characteristics of Nanjing has very important for guiding the local industrial and agricultural production and daily life. According to the daily data of precipitation and temperature of Nanjing station from 1955 to 2013, the paper used Db3 wavelet decomposition method, Man-Kendall method, Morlet wavelet analysis method and R/S analysis method to analyze the change tendency, periodic characteristics and long memory's property of the maximum daily precipitation, the days of precipitation in the year,the maximum daily temperature and minimum daily temperature in a year.The results show that the maximum daily precipitation, the days of precipitation, the maximum daily temperature and minimum daily temperature in a year is respectively showing an increasing, decreasing, increasing and increasing tendency now and in the future.Meanwhile, the main periods of before-mentioned indexes are 7, 22, 12 and 12 years respectively.These changes show that occurrence probability of drought and flood events in Nanjing will increase,which needs to attach great importance for the relevant departments.