Based on the framework SWMM hydrology and water quality model,the paper carried out sensitivity analysis for four kinds of land use which include 2 surface pollutant accumulation parameters and 2 surface pollutant eroding parameters, and identificated and selected the sensitivity parameters by using Morris screening method. It analyzed the correlation between simulation result with actual measurement one,and got the low sensitive parameters and high sensitive parameters of research area so as to improve the accuracy of simulation.