Hydrological data is the basis of engineering design and the consistency of its data directly influences the rationality of design results. The paper used the runoff data of the three station of Linjiacun, Xianyang and Huaxian in Weihe river of Shaanxi section from 1951 to 2010 to qualitatively analyzed and inspected the consistency of the sequence. By analyzing and contrast we concluded that the change of the trend, mutation and parameters of runoff series is not enough to show its change of consistency, need further inspection; the quantitative test showed that the mutation from 1969 to 1971 did not pass the consistency check of significance being 0.05, and the mutation in 1991-1994 is passed the significant consistency check for 0.05, witch shows that the change of the consistency of runoff series Shaanxi section of Weihe river took place during 1991 to 1994.