Hotan River is the third largest tributary of the Tarim River, the basin belongs to typical continental arid climate. Under the condition of practice rigidity water resources management, it is very important to protect water resources and prevent it from water pollution. Based on monitoring data for water quality from 2007 to 2010, the paper analyzed and predicted the water environment status and the future. By comparing with the pollution accommodation ,the result shows that the pollution drainage is still within the river's environment carrying capacity and will not deteriorate eco environment of the Hotan River. It finally put forward some control countermeasures.