Vitamins pharmaceutical wastewater was not able to meet the water quality requirements after a preliminary biochemical treatment because of the features with hard-biodegraded, high COD and ammonia nitrogen. According to these characteristics, the paper adopted hydrolysis acidification and aggrandizement with compound aeration→efficient and anaerobic combination reaction→displaced biological contact oxidation continuous process to deal with the wastewater of vitamin pharmaceutical deeply and study its feasibility. The medium-sized test which processing scale was 7.2 m3/d showed that hydrolysis acidification and aggrandizement with compound aeration process can be made B/C value raise from 0.33 to 0.48, improing next step''s biochemical treatment efficiency, when entering water CODcr concentration was 150 to 641 mg/L, ammonia nitrogen was 6 to 115 mg/L, the average removal rate can be achieved 84.28%, 93.8% respectively, the effluent water COD concentration can be less than 50 mg/L, ammonia nitrogen concentration can be less than 5 mg/L, achieved the first class of A of the Discharge Standard of Pollutants for Municipal wastewater Treatment Plant (GB18918-2002). Last of all, the continuous process on advanced treatment of such wastewater possess feasibility and stability.